\documentclass[12pt,border=5pt,tikz,class=scrartcl,multi=false]{standalone}
\usepackage{times}
\usepackage[T1]{fontenc}
\usepackage[latin1]{inputenc}
\usepackage{mathtools,amssymb,siunitx}
\usepackage{pgfplots}
\pgfplotsset{compat=1.13}

\usepackage{chemfig,chemmacros}
\renewcommand*{\familydefault}{\sfdefault}
\renewcommand*\printatom[1]{\ensuremath{\mathsf{#1} } }
\setatomsep{2em}
\setdoublesep{.6ex}
\setarrowdefault{,1,ultra thick}
\setbondstyle{very thick}
\definesubmol\nobond{-[,0.2,,,draw=none]}
\pagestyle{empty}
\thispagestyle{empty}
\begin{document}
%\renewcommand{\baselinestretch}{.5}
%\definesubmol\nobond{-[,0.25,,,draw=none]}
\schemedebug{false}
\schemestart[][west]
\chemleft[
\subscheme{
	\chemfig{
		*6(-=-=(-N~N)-=)
	}
}
\chemright]
\chemmove{
	\node[] at (0pt,85pt) {\ch{+} };
	\node[] at (12pt,65pt) {\ch{Cl-} };
}
\arrow{0}[,0.2]+\arrow{0}[,0.2]
\chemfig{
	R-S(=[2]O)(=[6]O)-NH_2
}
\arrow{->}
\chemfig{
	*6(-=-=
	(-N=[::-60]N-[::-60]N(!\nobond\chembelow[1ex]{}{H})
		-[::60]S(=[::90]O)(=[::-90]O)-[::0]R)
	-=)
}
\arrow{->[\ch{OH-}]}
\chemfig{
	*6(-=-=
	(-N=[::-60]\chemabove[0ex]{N}{\pch}=[::0]N\mch)
	-=)
}
\arrow{0}[,0]+\arrow{0}[,0.2]
\chemfig{
	\chemabove[0ex]{O}{\mch}-[::30]S(=[2]O)-[:-30]R
}
\schemestop
\end{document}